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Year : 2013  |  Volume : 13  |  Issue : 2  |  Page : 98-101

Injection of bone marrow concentrates for treatment of refractory tennis elbow

1 Department of Orthopaedics, Rohilkhand Medical College, Bareilly, Uttar Pradesh, India
2 Department of Physiotherapy, Jaipur College of Physiotherapy, Jaipur, Rajasthan, India

Correspondence Address:
Ajit Singh
Department of Orthopaedics, Rohilkhand Medical College, Pilibhit Bypass Road, Bareilly - 243 006, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1319-6308.123392

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Objective: The objective of this prospective study was the assessment of efficacy of bone marrow concentrate (BMC) (containing plasma rich in growth factors and mesenchymal stem cells) injection in treatment of refractory tennis elbow. Materials and Methods: A total of 30 adults with at least 6 months of refractory tennis elbow were administered single injection of BMC. This concentrate was made by centrifugation of iliac BM aspirate at 1800 rpm for 20-30 min and only upper layer containing platelet rich plasma and mononuclear cells was injected. Assessment was performed at baseline, 4 weeks and 12 weeks using Nirschl and visual analog scale (VAS) pain score. Results: Post-injection, significant reductions were reported in Nirschl, which decreased from a mean pre-injection score of 5.92 ± 0.85-3.19 ± 0.94 at 4 weeks (P < 0.001) and 1.65 ± 0.94 at 12 weeks (P < 0.0001). Similarly, significant reductions were found for VAS from a mean pre-injection score of 8.35 ± 0.94, to a mean VAS score of 5.23 ± 1.42 at 4 weeks (P < 0.0001) and to 1.85 ± 1.12 at 12 weeks (P < 0.0001). There were no adverse events. Conclusion: Treatment of patients with refractory tennis elbow with a single injection of BMC showed a significant improvement in short to medium term follow-up. This could be considered to be an alternative treatment for those patients who have failed non-operative treatment before surgical intervention is taken.

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